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KMID : 1148420180010010051
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Journal of Neurointensive Care
2018 Volume.1 No. 1 p.51 ~ p.54
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Concurrent Isolated Cortical Vein Thrombosis and Pulmonary Thromboembolism as an Initial Presentation of Protein S Deficiency: case report
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Han Kun-Hee
Choi Kyu-Sun
Ko Yong
Yi Hyeong-Joong
Song Dae-Hyo
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Abstract
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Protein S is a vitamin K-dependent anticoagulant protein. Its deficiency is a rare condition and can lead to deep vein thrombosis, pulmonary embolism or stroke. The incidence of cerebral venous thrombosis (CVT) is low, and in particular, isolated cortical vein thrombosis (ICVT) is very rare. Early diagnosis and treatment are quite important, as ICVT is potentially fatal. There are many known risk factors as pregnancy, puerperium, using oral contraceptive and etc. Here we report the case of a 59-year-old woman with isolated cortical vein thrombosis causing subarachnoid hemorrhage and intracerebral hemorrhage as clinical onset of Protein S deficiency. This case report discusses the possible mechanism and treatment of this extremely rare condition that is an association between ICVT and Protein S deficiency.
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KEYWORD
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Isolated cortical vein thrombosis , Pulmonary thromboembolism , Protein S deficiency
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